Biosciences research group

Overview

microbiology Research in the Biosciences Group focuses on microbiology, structural biology, physiology, cellular genomics and disease pathogenesis. Our research is broad and multidisciplinary within and beyond the School of Life and Medical Sciences with national and international collaborators.

The group is comprised of academics, research staff and full or part-time PhD and MRes students. Research in the biosciences unit is published in high-impact peer-reviewed scientific journals and is presented in national and international conferences.

Research areas

  • neuronsMicrobiology of infectious diseases, e.g. Clostridium difficile infection, antimicrobial agent development, and modelling the gut microflora/antimicrobial interactions (Dr Simon Baines)
  • Studying the molecular epidemiology and drug resistance detection in Mycobacterium tuberculosis. Discovery and development of novel antimicrobial agents against Mycobacterium tuberculosis and gram negative bacteria (Dr Madhu Goyal)
  • Investigation of phage-mediated virulence in Clostridium difficile and development of novel antimicrobial agents or strategies against human and animal pathogens such as Clostridium difficile, Escherichia coli, MRSA, Theileria species, and Mycobacterium bovis (Dr Shan Goh)
  • Understanding the molecular and cellular mechanisms that underlie human neurodegenerative diseases by using the nematode Caenorhabditis elegans (Dr Maria Dimitriadi)
  • Computational biochemistry and biophysics applied to viral infections and transmembrane protein-protein interactions (Dr Andreas Kukol)
  • Protein structure determination via NMR spectroscopy; recombinant protein expression and purification in bacterial and yeast expression systems; recombinant protein purification; biophysical analysis of proteins and interactions (Dr Pryank Patel)
  • Genetics, molecular biology and bioinformatics of disease pathogen carrying mosquitoes in relation to their control (Dr Colin Malcolm)
  • Muscle physiology and diseases of skeletal muscle (Dr Fang Lou)
  • Cancer Biology (Dr David Prowse)
  • Cell polarity in tissue and organ development (Dr Caroline Formstone)

Funding

Grants have recently been awarded from the Wellcome Trust, Royal Society, Procarta Bioscience Ltd and PRODEP Mexico.

Infrastructure

Research in the biosciences group is supported by the well-equipped state-of-the-art Science Building that houses cutting-edge research technologies: cell culture and histology facilities, standard molecular biology laboratories, fermentation equipment for medical microbiology and biotechnology research, confocal imaging and C. elegans microscopy.

Research degrees and post-doctoral fellowships

structural biologyApplications are invited from candidates with good first degrees in biology, genetics, neuroscience or other relevant disciplines to join projects as research students. Projects  for PhD and MSc by Research students are available, though not limited to, the areas mentioned above. In addition we welcome Visiting Researchers and Postdoctoral Fellowships in the research areas above. We will gladly support and assist with fellowship applications to national and international research councils or charities.

To learn more about the research degree programmes offered in biosciences please visit the Doctoral College page.

We recommend that you discuss your proposed research with a member of academic staff of the Biosciences Research Group before submitting your application. Please name the staff member when submitting your application.

For informal enquiries, please contact Dr Yongju Huang, Biological and Environmental Sciences Research Tutor.

Download your application form here. Application forms should be returned to Mrs Elizabeth Day, Research degrees administrator.